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Dr. James Wilson , House’s one true good friend, is the pinnacle of the Department of Oncology. Dr. Lisa Cuddy , an endocrinologist, is House’s boss, as she is the hospital’s dean of medication and chief administrator. House has a complex relationship with Cuddy, and their interactions typically contain a high diploma of innuendo and sexual rigidity. In the sixth episode of season 5 House & Home Improvement news, “Joy”, they kiss for the primary time. Their physical relationship does not progress any further during the fifth season; within the season- five finale, House believes he and Cuddy had intercourse, but it is a hallucination brought on by House’s Vicodin dependancy.